Vitamin D

Before Fertility Treatment

Article Written By:

Naturally Smart Team

Reviewed/Edited By:

Michael Feinman, MD, FACOG

Should I Take Vitamin D Before Fertility Treatment?

Great question! If you’re preparing for IVF or other fertility treatments, you’ve probably wondered if supplements can make a difference. Vitamin D is often called the “sunshine vitamin,” and it’s a vitamin that researchers are paying close attention to. We’ve compiled questions and answers based on recent research on Vitamin D.

Q: Can vitamin D really help with IVF success?

A: It might. A review of over 2,300 women found that those who took vitamin D before or during IVF were more likely to achieve a confirmed pregnancy. It didn't appear to reduce the risk of miscarriage, but it did seem to support those early, critical stages of conception — which is meaningful in itself.

Q: Who benefits the most?

A: Women with low vitamin D levels (below 30 ng/mL) appeared to gain the most benefit. And low vitamin D is far more common than most people realize. In modern life — with indoor work, limited sun exposure, and diets that rarely make up the difference — it's almost the default. Many people are deficient and have no idea. So before anything else, it's worth finding out where you actually stand, so checking your levels is a smart first step.

Q: How much should you take?

A: According to the research, daily supplementation in the range of 1,000–10,000 IU tended to outperform one-time high-dose approaches. Timing also mattered; starting 30 to 60 days before embryo transfer appeared to give the best results. That said, the right dose really does vary from person to person, so it's worth discussing with your doctor before you start.

Q: Should vitamin D be combined with other nutrients?

A: Some studies suggest it does. Vitamin D, paired with nutrients like folate and myo-inositol, showed promising results. That's part of why we formulated products like Methylfolate Plus and For Women's, to bring together the nutrients that come up most in fertility research, so you're not piecing it together on your own.

Q: Is vitamin D a guarantee for pregnancy?

A: No supplement can guarantee pregnancy. Vitamin D is just one piece of the fertility puzzle, but it may give your body extra support as you go through treatment.

 

Key Takeaway:

Vitamin D may help improve your chances of success with fertility treatment, especially if your levels are low. Talk to your doctor about testing your vitamin D and whether daily supplementation is right for you.

 

Source: Meng X, Zhang J, Wan Q, et al., Influence of Vitamin D supplementation on reproductive outcomes of infertile patients: a systematic review and meta-analysis., Reproductive Biology and Endocrinology (2023).

Disclaimer: This content is for educational purposes only and is not a substitute for personalized medical advice. Please consult your care team before making any changes to your supplement routine.

About the editor:

Dr. Michael Feinman.webp__PID:35c519a2-af24-4eed-b31f-e3175f0a7879

Dr. Michael Feinman is a retired reproductive endocrinologist and infertility specialist with over thirty-four years of experience. A pioneer in assisted reproductive medicine, he co-established the IVF program at Albert Einstein College of Medicine, led the first vaginal ultrasound-guided egg retrieval in New York, and helped create one of the first successful egg donor programs in the world. His career specialties included third-party parenting, minimal-stimulation and natural cycle IVF, and strategies for reducing multiple pregnancies.

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The Naturally Smart Vitamin D3 supplement is recommended to treat both male and female reproductive disorders, and may improve the neuromuscular and immune system. For those trying to conceive, Vitamin D3 appears to positively impact IVF outcomes, endometriosis, PCOS, and may boost levels of progesterone and estrogen. Can be taken in conjunction with fertility treatments.

Warning:

Pregnant or lactating women should consult with their physician prior to taking dietary supplements.

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