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The Naturally Smart Methylfolate Plus® formula is recommended by leading specialists in women’s health and reproductive medicine as an effective and easily absorbed folate supplement that’s ideal for pregnant or nursing women. It can also be beneficial for women who are currently undergoing fertility treatments, as part of their preparation for pregnancy.
Methylfolate is absolutely critical for fetal health. It plays an essential role in DNA and RNA synthesis, cell division, the manufacture of neurotransmitters and red blood cells, and the development of the nervous system. Studies show that a mother’s folate deficiency is linked to neural tube damage and birth defects such as spina bifida in her children. Supplementing with methylfolate is especially important because many women do not get adequate amounts of folate from diet alone—and may not process folic acid effectively.
The Naturally Smart Methylfolate Plus® formula contains L-methylfolate, pyridoxine (vitamin B6), and cyanocobalamin (vitamin B12), plus intrinsic factor—a glycoprotein critical to the absorption of vitamin B12. Taking these B vitamins together with intrinsic factor ensures better absorption and beneficial synergistic effects. Because L-methylfolate is water-soluble, any excess intake is typically excreted in urine, meaning there is a low risk of toxicity. However, it’s important to note that folate supplements may not be appropriate for all women.
Also, certain medical conditions can contribute to depleted folate levels. Supplementation may be especially important if you are pregnant or breastfeeding and have any of the following: liver disease, a need for kidney dialysis, a history of alcohol use disorder, certain types of anemia, or a malabsorption condition.
Please consult with your physician before use if you are taking any of the following medications: anticonvulsants, such as Dilantin, Phenytoin and Primidone; barbiturates; diuretics like Triamterene; Metformin (used to treat type 2 diabetes and Polycystic Ovarian Disease); Sulfasalazine (used to control inflammation associated with Crohn's disease and ulcerative colitis); and Methotrexate (used for the treatment of cancer, rheumatoid arthritis, and ectopic pregnancies).
Suggested Use:
Take 1 tablet daily with a glass of water or as advised by your health care professional. Can be taken with or without food.