Why Methylfolate Matters

Methylfolate, the active form of folic acid, is essential for a range of biological functions, including:

• DNA and RNA synthesis

• Cell division and repair

• Red blood cell production

• Neurotransmitter creation

• Nervous system development

During pregnancy, an adequate supply of methylfolate is especially important. Research shows that folic acid deficiency in mothers can increase the risk of neural tube defects, including spina bifida. Unfortunately, many women don’t get enough folic acid from diet alone—making supplementation a smart and often necessary step.

When Methylfolate Plus® May Be Especially Beneficial

In addition to pregnancy and breastfeeding, methylfolate supplementation may be helpful for women:

• Undergoing fertility treatments

• Managing malabsorption disorders
  

• Experiencing certain anemias
  

A Note on Medication Interactions

It’s important to talk to your healthcare provider before starting methyfolate, especially if you’re taking medications such as:

• Anticonvulsants (e.g., Dilantin, Phenytoin, Primidone)

• Barbiturates

• Diuretics (e.g., Triamterene)

• Metformin (for type 2 diabetes or PCOS)

• Sulfasalazine (for Crohn’s or ulcerative colitis)

• Methotrexate (used in cancer or autoimmune conditions)

Final Thoughts

Methylfolate Plus® offers a thoughtful, physician-recommended way to ensure optimal folate levels—supporting both maternal and fetal health. Whether you’re preparing for pregnancy, currently expecting, or nursing, talk to your healthcare provider to see if this supplement is right for you.